Dr. Sayem Miah is an assistant professor of the Department of Biochemistry and molecular biology, University of Arkansas for Medical Sciences (UAMS). He is also a full member of Winthrop P. Rockefeller Cancer Institute, UAMS. Now he is leading a research laboratory focusing on tyrosine kinase signaling in tumorigenesis and metastasis in the UAMS cancer research institute.

Dr. Miah received his doctoral studies in the laboratory of Dr. Kiven E. Lukong at the University of Saskatchewan, Saskatoon, Canada. During his doctoral studies, he demonstrated that the promotion of tumorigenesis by BRK in vivo primarily relies upon the full activation of BRK. He also showed that BRK targets the tumor suppressor Dok1 for proteasomal degradation to induce tumorigenesis.

For the postdoctoral training, Dr. Miah was drawn to the lab of Dr. Michael Washburn at the Stowers Institute for Medical Research (SIMR) for a “systems-wide” interrogation of signaling networks using innovative proteomic and genomic techniques. I showed that activated BRK directly interacts with and phosphorylates SMAD4 and causes proteasomal degradation to repress tumor suppressor gene FRK and to increase expression of the mesenchymal markers SNAIL and SLUG published in Sci. Adv.

He has authored and co-authored over 20 research articles, reviews, and book chapters. He received several awards, including Research excellence award KU Cancer Center Annual Research Symposium (2018), Saskatchewan Innovation and opportunity scholarships (2014).

Dr. Miah received a Bachelors and Master in Applied chemistry from the University of Rajshahi, Rajshahi, Bangladesh and Masters in Medical Biology from the University of Linkoping, Linkoping, Sweden.