UAMS Principal Investigator: Johnathan Goree, M.D., associate professor and director, Division of Chronic Pain, College of Medicine Department of Anesthesiology.
Summary: The Sequenced Strategy for Improving Outcomes in People with Knee Osteoarthritis (SKOAP) Study is a two-phase multi-site clinical trial comparing non-opioid pain management strategies. Phase 1 compares non-surgical treatments, including best practices, web-based pain-coping skills, and the use of duloxetine, an FDA-approved drug for joint pain. Phase 2 compares joint injections, nerve blocks and nerve ablations to treat participants’ knee osteoarthritis.
Significance: Researchers hope the study of non-surgical, non-opioid pain treatments will reveal the best way to reduce knee osteoarthritis pain and improve function.
TRI Services: Medicare coverage analysis, study budget development, administration of Clinical Trial Management System, clinical research coordinator support, and post-award financial management.
Sponsor: Johns Hopkins University; funding by the Helping to End Addiction Long-term® (HEAL) Initiative; administered by the CTSA Trial Innovation Network.