Topics: Scientific Concepts and Research Design

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Which statistical tests should I use?

Last Modified: February 10, 2022
The objectives of this course are to: describe the basics of hypothesis testing; compare and contrast t-tests, paired t-tests, and chi-square tests; and list factors to consider when determining when...

What would happen if we change the way we talk about our research?

Last Modified: February 10, 2022
Tracy Mehan, Nationwide Children's Hospital, talks about changing the way we talk about research and accessibility. https://www.youtube.com/watch?v=AozDsrWzgIQ&feature=youtu.be

To Resubmit or Not – When Your Proposal Isn’t Funded

Last Modified: February 10, 2022
This seminar and panel discussion will focus on best practices for surviving peer review and successfully resubmitting an NIH proposal. Seasoned PIs will review reasoning and rationale behind changes...

Toolkit for Developing Community Partnerships

Last Modified: February 10, 2022
This toolkit is intended to be a resource for researchers, health care providers and the community who are interested in conducting community-engaged research. This community partnership toolkit outl...

The Role of Machine Learning in Predictive and Causal Inference

Last Modified: February 10, 2022
https://www.youtube.com/watch?v=po2qo-PDuns&list=PL0UcWim64fqnDLMaWNVPJJkpQRyfqaV5u&index=6

Mixed Methods (2 of 4): The Qualitative Research Process: Study Designs for Health Services Research

Last Modified: February 10, 2022
The objectives of this course are to: identify core components of a qualitative study design, including the importance of a primary research question and approach to the study; determine the appropri...

The Art and Science of Clinical Trial Feasibility with Industry Experts from BBK Worldwide

Last Modified: February 10, 2022
Clinical trial feasibility – it’s a standard part of recruitment planning and essential for predicting enrollment success. Yet so often it’s easy to get wrong, putting timelines and budget at risk. A...

Team Science (COALESCE)

Last Modified: February 10, 2022
COALESCE is a free online team science educational resource developed by Northwestern University researchers and designed to foster cross-disciplinary, collaborative research in the health sciences. ...

Systematic Review, Advance-CTR

Last Modified: February 10, 2022
In this half-day course, experts from Brown’s School of Public Health will discuss: The role and value of systematic reviews, the basic steps involved in conducting a systematic review, and how th...

Stakeholder Engagement in Patient-Centered Comparative Effectiveness Research

Last Modified: February 10, 2022
What is stakeholder and community engagement (SCE), and why is it important? Learn the benefits, strategies, and methods at Stakeholder Engagement in Patient-Centered Comparative Effectiveness Resear...

Stakeholder Engagement in Basic Science: Theory to Practice

Last Modified: February 10, 2022
When you spend most of your research in a lab, the idea of engaging stakeholders in research may not seem tangible or practical. In this course, Thomas Concannon, PhD, Co-Director of Tufts CTSI Stake...

“Role of Calibration in Uncertainty-based Referral for Deep Learning” & “Supervised Machine Learning Workflows for Electronic Health Records”

Last Modified: February 10, 2022
Ruotao Zhang, MSc: “Role of Calibration in Uncertainty-based Referral for Deep Learning” The uncertainty in predictions from deep neural network analysis of medical imaging is challenging to assess b...

REDCap: Introduction to e-Consent

Last Modified: February 10, 2022
This workshop covers the ins & outs of using REDCap for e-consenting research participants and provides a guided demonstration of the e-Consent template. Participants will learn how to design and...

REDCap Features, Tips, & Tricks

Last Modified: February 10, 2022
REDCap is designed to be largely self-taught when it comes to the basics. We strongly recommend you view some of the available introductory videos noted below before taking one of our REDCap classes....

REDCap Advanced Users Series: Randomization

Last Modified: February 10, 2022
This webinar clears up the common misconception that REDCap randomizes your participants for you (Spoiler: it doesn't), and gives you all the tools you need to use the randomization module with your ...

Rare Disease Research

Last Modified: February 10, 2022
This talk focuses on clinical research in rare diseases. https://www.youtube.com/watch?v=3VNIm8bmxUQ

Qualitative Methods Series “The Power of Designing with Patients”

Last Modified: February 10, 2022
“The Power of Designing with Patients” Presented by Aaron J. Horowitz Co-Founder & CEO, Sproutel. Aaron is a maker; from sculptures to business, he is fascinated with the process of taking an ide...

Preparing for Patient-Centered and Stakeholder-Engaged Research

Last Modified: February 10, 2022
Learn how to make your research patient-centered, and find out how engagement fits into your research process at Preparing for Patient-Centered and Stakeholder-Engaged Research. Thomas Concannon, PhD...

Precision Medicine

Last Modified: February 10, 2022
This talk reviews methods and issues in precision medicine. https://www.youtube.com/watch?v=VymkM5KZkDc

Practice Oriented Research Training (PORT)

Last Modified: February 10, 2022
The Practice Oriented Research Training program (PORT) was developed to meet the needs of practicing clinicians who want to become competent and active members of the research enterprise. The program...

Planning and Evaluation of Stakeholder Engagement in Research

Last Modified: February 10, 2022
This lecture provides researchers with practical guidance for carrying out and evaluating multi-stakeholder engaged research projects. The material presented can assist researchers to consider more s...

Pediatric Rare Diseases

Last Modified: February 10, 2022
Pediatric Disease and Clinical Trials Click here to download course slides.

Pediatric and Rare Disease Study Designs

Last Modified: February 10, 2022
The content in this course was presented on April 18, 2018 in Washington, D.C., as part of the Association for Clinical and Translational Science (ACTS) 2018 meeting. This course requires enrollme...

Oncology Clinical Trials Conference

Last Modified: February 10, 2022
The purpose of this workshop is to assist Research Professionals in improving their skills and their understanding of the responsibilities of conducting oncology clinical research. The goal will be a...

Office for Human Subjects Protection Core Training – Module 7 Investigational Products

Last Modified: February 10, 2022
The goal of the core training modules is to cultivate advanced understanding of research topics. Each of the ten learning modules covers a different topic area. View course here.

Office for Human Subjects Protection Core Training – Module 5 Recruitment and Retention

Last Modified: February 10, 2022
The goal of the core training modules is to cultivate advanced understanding of research topics. Each of the ten learning modules covers a different topic area. View course here.

Modeling Time-to-Event Outcomes

Last Modified: February 10, 2022
The objectives of this course are to: define survival analysis Explain how time-to-event data is different from other data, discuss the differences between Kaplan-Meier curves and Cox regression, ide...

Methods for Prioritizing Research in Comparative Effectiveness Research

Last Modified: February 10, 2022
This training will discuss prioritizing resources and go over the question "are we studying what matters?" This course requires enrollment in Tufts CTSI iLearn. Enroll in course here.

Linear and Logistic Regression

Last Modified: February 10, 2022
The course objectives are to: determine when regression should be used, describe the differences between linear and logistic regression, discuss basic assumptions of linear and logistic regression, i...

Investigational Drugs and Devices (IND / IDE) Assistance

Last Modified: February 10, 2022
This online course is intended to provide access to training and continuing education that will promote quality clinical research, protect the welfare of research participants and improve global heal...

Introduction to Machine Learning

Last Modified: February 10, 2022
Presented by: Carsten Eickhoff, PhD, assistant professor of medical and computer science at Brown University This talk introduces the basic components of machine learning systems and research papers ...

Introduction to Human Subjects Research

Last Modified: February 10, 2022
Recorded 2009 Presenter: Tani Prestage Objectives- Learn about regulations and ethical principles for human subjects research; Clarify differences between what is human subjects research and what is ...

Introduction to Electronic Consent

Last Modified: February 10, 2022
The Michigan Institute for Clinical & Translational Research (MICHR) provides supplemental training on the basics of electronic informed consent. This self-guided course is about the process of u...

Introduction to Clinical and Translational Research: Study Population and Study Design

Last Modified: February 10, 2022
This course outlines basic concepts and terminology in the design of clinical/translational research projects targeting specific populations, and discusses methods to identify useful study population...

Introduction to Clinical and Translational Research: Statistical Model and Systematic Reviews

Last Modified: February 10, 2022
The first section of this video lecture series discusses the process of developing a conceptual and statistical model that can most effectively test a hypothesis. The second section describes the rol...

Introduction to Clinical and Translational Research: Bias in Clinical/Translational Research: Analyzing Data and Interpreting the Results

Last Modified: February 10, 2022
In the first section, lectures cover potential sources of bias that can occur at all stages of research, and how to mitigate their impact on findings. The second section focuses on analysis of data i...

Introduction to Clinical and Translational Research

Last Modified: February 10, 2022
This course introduces the mission and processes of Clinical and Translational Research (CTR). It demonstrates approaches to formulating and writing research questions and hypotheses appropriate to C...

Interpretable Individualized Treatment Rules Using Decision Lists

Last Modified: February 10, 2022
Presented by Yichi Zhang, PhD, assistant professor in the Department of Computer Science and Statistics at the University of Rhode Island. Precision medicine is currently a topic of great interest in...

ICH GCP E6 (R2): From the site’s perspective

Last Modified: February 10, 2022
The International Council for Harmonisation (ICH) published a revision to GCP E6 based on feedback from the global clinical research community, advancements in technology and risk management developm...

I2S2 Seminar: Use of OpenMRS Open Source EHR to Support COVID-19 Management in Haiti, Nepal & Kenya

Last Modified: February 10, 2022
Managing COVID-19 requires accurate up to date data on new cases, contact tracing and case management. Managing epidemic diseases is a core function of health systems in many low and middle income co...

I2S2 Seminar Series: Clinical Decision Support Deconstructed

Last Modified: February 10, 2022
I2S2 Seminar Series: Clinical Decision Support Deconstructed – What Works? How Does It Work? What’s New? Featuring Jonathan Teich, MD, PhD. Clinical decision support (CDS) provides clinicians and pat...

I2S2 Seminar: Rhode Island @ AMIA Year in Review

Last Modified: February 10, 2022
I2S2 covers the breadth of topics in effectively using data and technology to advance biomedical discovery and healthcare delivery. Each learning activity (seminar, journal club, workshop, or tutoria...

I2S2 Seminar: Clinical AI From Time Series to Free Text

Last Modified: February 10, 2022
Data-driven clinical decision making, e.g., via machine learning, holds considerable promise for evidence based medicine. This session will present three ongoing advances from BCBI’s AI Lab that tack...

Health Disparities and Mentoring

Last Modified: February 9, 2022
Tamekia Smith, Nationwide Children's Hospital, discusses issues of health disparities and the need for mentoring and issues of health equity and social determinants of health. https://www.youtube...

Fundamentals of Clinical and Translational Science (FunCaTS)

Last Modified: February 9, 2022
Fundamentals of Clinical and Translational Science (FunCaTS) is a combination of 13 online modules strategically packaged together to enable medical professionals and allied health staff to expand th...

Formulating Research Questions, Hypotheses and Objectives

Last Modified: February 9, 2022
The objectives of this course are: outline approach to formulating structured, clinically-relevant research questions; highlight importance of evidence based approach to critically evaluating scienti...

Expert Feedback on NIH Rigor and Transparency Guidelines

Last Modified: February 9, 2022
This course presents expert discussion held in 2016 on NIH Rigor and Transparency Guidelines, led by John Castellot, PhD, Tufts CTSI Navigator and NIH Study Section Chair, and Amy Gantt, MA, Tufts Un...

Experimental and Observational Study Designs

Last Modified: February 9, 2022
The objectives of this course are: identify if a research study is observational or experimental, describe when to use an observational study design versus an experimental study design, discuss the d...

Exempt Research

Last Modified: February 9, 2022
The objectives of this course are to: define the categories of exempt research, review the exempt review process, and review examples of research that is and is not exempt. View course here.

Evaluating Medical Journal Articles

Last Modified: February 9, 2022
The objectives of this course are to: identify the specific, testable hypotheses of the study; identify the study design; determine how the data were collected; evaluate whether the results were affe...

Engaging Patients through Technology – Advancing the Intersection of Consumer Health Informatics and Implementation Science

Last Modified: February 9, 2022
Engaging Patients through Technology - Advancing the Intersection of Consumer Health Informatics and Implementation Science presented by Timothy Hogan, PhD. Patient-facing technologies, including mhe...

Developing a Study Protocol

Last Modified: February 9, 2022
The objectives of this course are to: define a research protocol, explain the difference between a protocol and a proposal, list the steps in planning a study, identify potential issues in implementi...

Developing and Writing the Protocol

Last Modified: February 9, 2022
This module describes who can assist you in developing and writing the protocol, the contents of the protocol elements, and tips for specific types of studies. View course here.

Developing a Community Advisory Board for Research Toolkit

Last Modified: February 9, 2022
More and more, grant proposals are requesting researchers to ensure that they have worked with or plan to integrate the community into their research proposal. One approach to this is to develop a co...

Mixed Methods (3 of 4): Designing a Mixed Methods Study

Last Modified: February 9, 2022
The objectives of this course are: describe how a combination of qualitative and quantitative methods can contribute to answering research questions, identify ways to combine quantitative and qualita...

Data Structure with REDCap: Active Design Rather Than Passive

Last Modified: February 9, 2022
Many users are not aware that they can choose what their database looks like in REDCap -- the key is to make those choices before you get started using REDCap's features. https://www.youtube.com/...

Cross-Study Machine Learning Techniques: Reproducibility and Differences Across Studies

Last Modified: February 9, 2022
Presented by Roberta De Vito, PhD, assistant professor of biostatistics and data science at Brown University. Biostatistics and computational biology are increasingly facing the urgent challenge of e...

Conducting Research with Biorepositories

Last Modified: February 9, 2022
https://www.youtube.com/watch?v=JSvg5eZ6A9w&list=PLkw6pa7n2OjX1AnXcG0L_5IAvNEvkyusp

Community-Engaged Research 101

Last Modified: February 9, 2022
In this video, an SC CTSI specialist introduces the basic characteristics of community-engaged research and the rationale for this research approach, including the development of health solutions amo...

Clinical Research / Clinical Science Course

Last Modified: February 9, 2022
This course has been established to develop an internationally accepted standard of knowledge and understanding of the research process and related regulations, as well as medical and scientific area...

Clinical Natural Language Processing, Some Tasks and Applications in Medicine

Last Modified: February 9, 2022
In this talk, Professor Savova will position the latest developments in clinical Natural Language Processing (NLP) in the context of the explosive achievements in the broader NLP field. How can clini...

Can design help medicines fail faster?

Last Modified: February 9, 2022
Robert Strouse, Nationwide Children's Hospital, discusses how failure in research is not negative, lessons learned from research failure helps us learn and move forward. https://www.youtube.com/w...

Calculating Sample Size and Power

Last Modified: February 9, 2022
The objectives of this course are to: explain the role of chance in sampling a population, describe what parameters affect sample size, list online resources for sample size calculators, and perform ...

Bluffing Cancer: Story of Drug Discovery

Last Modified: February 9, 2022
Dr. Tim Cripe, Nationwide Children's Hospital, discusses issues related to drug discovery in cancer research. https://www.youtube.com/watch?v=vuhQy06cekg&feature=youtu.be

Biostatistics Core Seminar Series: “Experimental Study Design”, Advance-CTR

Last Modified: February 9, 2022
Advantages and disadvantages of experimental studies, individual vs. group trials, preventive vs. therapeutic trials, parallel RCTs, factorial study design, new drug trials, sources of potential bias...

Biostatistics Core Seminar Series: “Cohort Studies & Case-Control Studies”, Advance-CTR

Last Modified: February 9, 2022
Advantages and disadvantages of cohort studies, prospective vs. retrospective cohorts, types of analyses used in cohort studies, sources of potential bias Advantages and disadvantages of case-cont...

Biostatistics Core Seminar: “Inference with Categorical Variables”, Advance-CTR, Brown University

Last Modified: February 9, 2022
Topic: Inference with categorical variables: Contingency tables, degrees of freedom, chi-square, fisher’s exact test https://www.youtube.com/watch?v=rADdSnz9QD4

Biostatistics Core Seminar: “Hypothesis Testing”, Advance-CTR, Brown University

Last Modified: February 9, 2022
Topic: Hypothesis TestingNull hypotheses, type I and II error, significance level, power, basic sample size calculation https://www.youtube.com/watch?v=ocOjN_PSPgs

Biostatistics and Computation for Addiction Data Analysis

Last Modified: February 9, 2022
Interested in learning about novel data analysis methods and tools for addiction research? To better understand the science of addiction disorders, the research community needs continuous development...

Best Practices for Social and Behavioral Research

Last Modified: February 9, 2022
Good Clinical Practice (GCP) is an international ethical and scientific quality standard for designing, conducting, recording and reporting clinical trials. The principles of GCP help assure the safe...

ASA Evidence Synthesis & Meta-Analysis, Two Day Workshop

Last Modified: February 9, 2022
In this two day workshop presented by the American Statistical Association (ASA), Hawai’i Chapter at University of Hawai‘i at Mānoa on June 5 & 6, 2019, Christopher H. Schmid, PhD presents on the...

Bedside Nursing – The Journey from Point A to Point B: How to get from Clinical Inquiry to Conducting Nursing Research

Last Modified: February 9, 2022
This online course is intended to define three types of clinical inquiry: evidence based practice (EBP), quality improvement (QI), and research. Steps nurses can take to move from having a practice i...

Bedside Nursing

Last Modified: February 9, 2022
This online course will provide information on the purpose and components of a research protocol and helpful strategies for writing a protocol draft with an Institutional Review Board reviewer’s pers...

Mixed Methods (4 of 4): Applying Mixed Methods Effectively

Last Modified: February 9, 2022
The objective of this course is to: summarize the study design used in a mixed methods research study, explain the rationale for using a mixed methods approach, identify the tools employed in a mixed...

Mixed Methods (1 of 4): An Introduction to Mixed Methods

Last Modified: February 9, 2022
The objectives of this course are to determine which sessions in this seminar series will be helpful to you and to identify potential opportunities for mixed methods approaches in health services res...

An Overview of Survey Design

Last Modified: February 9, 2022
The objectives of this course are to: define the purpose of survey research, describe key considerations in designing a survey instrument, identify types of questions and response options to gather r...

Applying Implementation Science Frameworks to Your Research

Last Modified: February 9, 2022
This short course provides an overview of two common implementation frameworks used in grant proposals, RE-AIM (the Reach, Effectiveness, Adoption, Implementation, and Maintenance Framework) and CFIR...

Applying Concept Mapping Methodology To Understand Resilience Resources Among African Americans Living With HIV In The Southern United States

Last Modified: February 9, 2022
Advance-CTR Qualitative Methods Series “Applying Concept Mapping Methodology To Understand Resilience Resources Among African Americans Living With HIV In The Southern United States” Presented by Aki...

A Perspective on the Current State of Clinical Research Education and Training

Last Modified: February 9, 2022
This is a peer-reviewed article by Beth Harper of ACRP that provides a comprehensive picture of training and education in clinical research, professional roles, identities and competencies in clinica...

An Introduction to Rapid Ethnography: Its Applications and Utility in Public Health Research

Last Modified: February 9, 2022
Advance-CTR Qualitative Methods Series "An Introduction to Rapid Ethnography: Its Applications and Utility in Public Health Research" Presented by Alexandra Collins, PhD Postdoctoral Research Associa...

Advanced REDCap: Longitudinal Survey Studies

Last Modified: February 9, 2022
Advanced REDCap: Longitudinal Survey Studies virtual workshop with Sarah B. Andrea, PhD, MPH. This class is for intermediate to advanced users (prerequisite: Introduction to REDCap) This class covers...

Addicted to Love: Babies born with opioid addiction

Last Modified: February 9, 2022
Dr. Barry Halpern, Nationwide Children's Hospital, discusses his experiences with treating opioid addicted neonates, understanding addition in this Ted Talk. https://www.youtube.com/watch?v=UGGcw...