The Comprehensive Research Informatics Suite (AR-CRIS) is a set of open-source software tools for electronic management of research data. The software programs can function together to facilitate data collection, event tracking and study center operations.
All components of AR-CRIS are web based, enabling sharing and integration of clinical research information for single and multi-site projects. All applications are integrated into a portal that allows single point of access with a registered UAMS username and password.
You can request assistance with the tools below via the Request Services button, this page:
Adverse Event Reporting: The Adverse Event Reporting System (AERS) is a tool for tracking and assessing adverse events (AEs) throughout the course of a study. It has the capacity to import laboratory-based AEs as well as push AE information to EPIC and OpenClinica. The Cancer Adverse Event Reporting System (caAERS) also includes AE report definitions and supports electronic AE submissions to the National Cancer Institute.
Biological Specimen Tracking: caTissue is a biorepository tool for biospecimen inventory management, tracking and annotation. It permits users to enter and retrieve data on the collection, storage, quality assurance and distribution of biospecimens. The application is currently used by the UAMS Tissue Procurement Facility, which coordinates and oversees the donation, processing, storage and dissemination of tissue specimens and related data.
Electronic Data Capture: OpenClinica is a 21 CFR part 11-compliant application for electronic data capture. The application supports data submission, validation, annotation, filtering and extraction as well as study oversight, auditing and reporting. It has sophisticated data security controls, allowing role-based access. CIRC staff have extensive experience creating common data elements and standardized electronic case report forms for investigators to use with OpenClinica.
Free Text Extraction: caTIES enables de-identification and automated coding of free-text structured reports. It provides researchers with the ability to query, browse and acquire annotated tissue data and physical material across a network.
Subject Registration: The Research Participant Registry System (RPRS) enables efficient and streamlined registration of research participants. The tool captures the date of informed consent, eligibility criteria, screen failures, stratification, randomization and amendments. Clinical workflows are enabled by both subject- and study-centric views into the registration process. Registration data can be pulled from EPIC to minimize manual data entry and enhance data quality.
Study Calendar Management: Patient Study Calendar (PSC) is a standards-compliant application for creating and managing subject activities and study calendars. It provides the ability to create and edit study calendar templates, generate and view prospective calendars of subject activities, track activities as they occur, and manage subject calendars as they change during a study.
Surveys & Instruments: LimeSurvey is a robust and user-friendly application for creating online surveys. It enables users to quickly create surveys, deliver questionnaires to respondents, collect responses, and analyze or export results in various formats.
Tracking Regulatory Events: EventTracker is an application for tracking key regulatory dates such as IRB submissions, approvals and renewals. The tool also includes an Electronic Delegation Log